If you're missing a day without a bowel movement, this means toxins are increasing in the body, which will lead to inflammation in the GI tract, as well as joints, muscles or even nerves in the future. The long term effects of constipation, results in fatigue, inflammation, pain, headaches, and nutritional deficiencies, as well as structural changes in the colon (diverticuli.) Additionally, constipation can obstruct the urinary flow and can lead to recurrent bladder or urinary tract infections. Fortunately, herbal treatments, supported by the right diet and good eating habits, can resolve constipation in a matter of weeks. Constipation therapy.